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Research in the lab is focused on understanding the molecular genetic mechanisms that control how genes are turned on and off. To do this we predominantly study two experimental systems:

• The first focuses on the human pathogen Talaromyces marneffei, a small eukaryotic fungus that infects humans and ultimately leads to death of the infected host if untreated. By understanding how the fungus infects humans and causes disease we can develop strategies to control and combat fungal diseases.
• The second focuses on the model organism Aspergillus nidulans, a small eukaryotic fungus that has been used to understand the molecular and cellular mechanisms of many biological processes common to eukaryotes from fungi to humans.

In addition to the fundamental knowledge about how organisms function, the work also has important implications for developing new or improved applications for the use of fungi in biotechnology.