Yang is currently working at PEARG as a population geneticist with a focus on insecticide resistance management in red legged earth mites. In the past, her research has largely focused on using techniques of molecular biology and biochemistry to understand role of ceramide-metabolism enzymes in insect development and longevity. During her PhD in Zhejiang University, China, she reported the cloning, biochemical characterization, and functional analysis of Drosophila alkaline ceramidase (Dacer), suggesting that Dacer plays an important role in the Drosophila development and longevity by controlling the metabolism of ceramides. She then worked as a research fellow in Jiangsu academy of agricultural sciences, China, characterizing ceramidase and sphingomyelinase in Chilo suppressalis. She was also involved in transcriptome analysis of Scirpophaga incertulas with focus on bet-hedging genes. From 2014, Yang shifted focus into population genetics where she explored fine-scale processes of gene flow and dispersal in resistant red legged earth mites. This knowledge can be applied to better understand the routes resistant individuals have dispersed along, that may be important in reducing the risk of resistance spreading further.
Insecticide resistance management (population genetics) in red legged earth mites
NHMRC Dengue Program
Refereed Journals (first author)
Yang Q, Sun N, Zheng M, Luo CC, Luo GH, Fang JC*，Construction of genomic ddRADseq libraries of Chilo suppressalis and Scirpophaga incertulas (Lepidoptera: Pyralidae). Nature Enemies of Insects, 2016 (6): 1114-1120.
Yang Q, Li XW, Lin XW, Zhou Y, Yuan JQ, Wang HD, Chen JA, Mao CG , Zhu ZR*, Characterization of free endogenous sphingoid bases in the golden apple snail Pomacea canaliculata: involvement in snail development and nutrient limitation. Invertebrate Reproduction & Development, 2013, 57(4): 287 – 292.
Yang Q, Zhou Y, Han GJ, Fang JC*. Isolation, identification and active ingredient analysis of two pathogenic bacterial strains from Scirpophaga incertulas (Lepidoptera: Pyralidae). Jiangsu Journal of Agricultural Science. 2012, 28(6): 1267-71.
Yang Q, Gong ZJ, Zhou Y, Yuan JQ, Cheng JA, Tian L, Li S, Lin XD, Xu RJ, Zhu ZR* Mao CG*, Role of Drosophila alkaline ceramidase (Dacer) in Drosophila development and longevity. Cellular and Molecular Life Sciences, 2010, 67(9): 1477-1490.
Refereed Journals – co-author
Zhang YL, Han YC, Liu BS, Yang Q, Guo HF, Liu ZW, Wang LH, Fang JC*, Resistance monitoring and cross-resistance role of CYP6CW1 between buprofezin and pymetrozine in field populations of Laodelphax striatellus (Fallen). Scientific Reports, 2017, 7: 14639.
Zhou Y, Lin XW, Begum MA, Zhang CH, Shi XX, Jiao WJ, Zhang YR, Yuan JQ, Li HY, Yang Q, Mao CG, Zhu ZR*, Identification and characterization of Laodelphax striatellus (Insecta: Hemiptera: Delphacidae) neutral sphingomyelinase. Insect Molecular Biology, 2017, 6(4): 392-420.
Luo GH, Yao J, Yang Q, Zhang ZC, Hoffmann AA, Fang JC*, Variability in development of the striped rice borer, Chilo suppressalis (Lepidoptera: Pyralidae), due to instar number and last instar duration. Scientific Reports, 2016, 6: a35231.
Rašic G*, Endersby-Harshman NM, Tantowijoyo W, Goundar A, White VW, Yang Q, Filipovid I, Johnson P, Hoffmann AA, Arguni E, Aedes aegypti has spatially structured and seasonally stable populations in Yogyakarta, Indonesia. Parasites and Vectors, 2015, 8: 610.
Zhou Y, Yang Q, Han GJ, Fang JC*, Isolation of genomic microsatellite molecular markers with enrichment of suppression-PCR in Scirpophaga incertulas (Lepidoptera: Pyralidae). Jiangsu Journal of Agricultural Science, 2013, 29(5): 999-1004.
Zhang YL, Guo HF, Yang Q, Li S, Wang LH, Zhang GF, and Fang JC*. Overexpression of a P450 gene (CYP6CW1) in buprofezin-resistant Laodelphax striatellus (Fallén). Pesticide Biochemistry and Physiology, 2012, 104 (3): 277-282.
Zhou Y, Lin XW, Yang Q, Zhang YR, YuanJQ, Ling XD, Xu RJ, Cheng JA, MaoCG*, Zhu ZR*. Molecular cloning and characterization of neutral ceramidase homologue from the red flour beetle, Tribolium castaneum. Biochimie, 2011, 93 (7): 1124-1131.